HFE Rabbit Polyclonal Antibody

CAT#: TA327033

HFE Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using HFE antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human HFE
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: hemochromatosis
• Database Link:
  NP_000401
  Entrez Gene 15216 MouseEntrez Gene 3077 Human
  UniProt ID Q30201
• Background: The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
• Synonyms: HFE1; HH; HLA-H; MVCD7; TFQTL2

Reference Data

• Protein Families: Druggable Genome, Transmembrane