Heme Oxygenase 1 (HMOX1) Rabbit Polyclonal Antibody

CAT#: TA327035

Rabbit anti-HMOX1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using HMOX1 antibody.

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  Immunohistochemistry of paraffin-embedded human kidney cancer using HMOX1 antibody at dilution of 1:100 (400x lens).

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human HMOX1
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: heme oxygenase 1
• Database Link:
  NP_002124
  Entrez Gene 15368 MouseEntrez Gene 24451 RatEntrez Gene 3162 Human
  UniProt ID P09601
• Background: Heme oxygenase (HO) is the rate-limiting enzyme in the catabolism of heme that results in the release of carbon monoxide, iron, and biliverdin. The products of this enzymatic reaction play important biological roles in antioxidant, anti-inflammatory and cytoprotective functions. Heme oxygenase comprises two isozymes, including the constitutively expressed HO-2 isozyme and the inducible HO-1 isozyme. Inducible HO-1 is expressed as an adaptive response to several stimuli, including heme, metals, and hormones. The induction of HO-1 has been implicated in numerous disease states, such as transplant rejection, hypertension, atherosclerosis, Alzheimer disease, endotoxic shock, diabetes, inflammation, and neurological disorders.
• Synonyms: bK286B10; HMOX1D; HO-1; HSP32

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Porphyrin and chlorophyll metabolism