CES2 Rabbit Polyclonal Antibody

CAT#: TA327057

Rabbit anti-CES2 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using CES2 antibody.

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  Immunofluorescence analysis of MCF-7 cell using CES2 antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, WB
• Recommended Dilution: WB 1:500 - 1:2000;IF 1:50- 1:200
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide of human CES2
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: carboxylesterase 2
• Database Link:
  NP_003860
  Entrez Gene 8824 Human
  UniProt ID O00748
• Background: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: CE-2; CES2A1; iCE; PCE-2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - other enzymes