alpha 2 Macroglobulin (A2M) Rabbit Polyclonal Antibody

CAT#: TA327083

A2M Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using A2M antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide of human A2M
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 163 kDa
• Gene Name: alpha-2-macroglobulin
• Database Link:
  NP_000005
  Entrez Gene 24153 RatEntrez Gene 2 Human
  UniProt ID P01023
• Background: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008]
• Synonyms: A2MD; CPAMD5; FWP007; S863-7

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades