MAD2 (MAD2L1) Rabbit Polyclonal Antibody

CAT#: TA327145

Rabbit anti-MAD2L1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using MAD2L1 antibody.

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  Immunohistochemistry of paraffin-embedded human rectal cancer using MAD2L1 antibody at dilution of 1:100 (200x lens).

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  Immunohistochemistry of paraffin-embedded rat testis using MAD2L1 antibody at dilution of 1:100 (200x lens).

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human MAD2L1
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: MAD2 mitotic arrest deficient-like 1 (yeast)
• Database Link:
  NP_002349
  Entrez Gene 56150 MouseEntrez Gene 297176 RatEntrez Gene 4085 Human
  UniProt ID Q13257
• Background: MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.
• Synonyms: HSMAD2; MAD2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation