DCK Rabbit Polyclonal Antibody

CAT#: TA327178

Rabbit anti-DCK Polyclonal Antibody

Product Images

Western blot analysis of extracts of WiDr cell lines, using DCK antibody.

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  Immunohistochemistry of paraffin-embedded mouse kidney using DCK antibody at dilution of 1:100 (200x lens).

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  Immunohistochemistry of paraffin-embedded rat kidney using DCK antibody at dilution of 1:100 (200x lens).

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  Immunohistochemistry of paraffin-embedded rat lung using DCK antibody at dilution of 1:100 (200x lens).

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  Immunofluorescence analysis of MCF7 cell using DCK antibody. Blue: DAPI for nuclear staining.

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Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200;IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human DCK
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: deoxycytidine kinase
• Database Link:
  NP_000779
  Entrez Gene 13178 MouseEntrez Gene 79127 RatEntrez Gene 1633 Human
  UniProt ID P27707
• Background: Deoxycytidine kinase (dCK) is required for the phosphorylation of several deoxyribonucleoside analogues that are widely employed as chemotherapeutic agents. It is also a key enzyme in the phosphorylation of a variety of antineoplastic and antiviral nucleoside analogs including cytosine arabinoside (araC) and dideoxycytidine (ddCyd); deficiency of deoxycytidine kinase activity mediates resistance to these drugs. This protein can exsit as a homodimer. This antibody is specific to DCK.
• Synonyms: MGC117410; MGC138632

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Purine metabolism, Pyrimidine metabolism