Phospholipase C beta 1 (PLCB1) Rabbit Polyclonal Antibody

CAT#: TA327224

PLCB1 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of NCI-H460 cell lines, using PLCB1 antibody.

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  Immunohistochemistry of paraffin-embedded human breast cancer using PLCB1 antibody at dilution of 1:200 (400x lens).

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  Immunohistochemistry of paraffin-embedded rat lung using PLCB1 antibody at dilution of 1:200 (400x lens).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human PLCB1
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: phospholipase C beta 1
• Database Link:
  NP_056007
  Entrez Gene 18795 MouseEntrez Gene 24654 RatEntrez Gene 23236 Human
  UniProt ID Q9NQ66
• Background: The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• Synonyms: EIEE12; PI-PLC; PLC-154; PLC-I; PLC154; PLCB1A; PLCB1B

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway, Chemokine signaling pathway, Gap junction, GnRH signaling pathway, Huntington's disease, Inositol phosphate metabolism, Long-term depression, Long-term potentiation, Melanogenesis, Metabolic pathways, Phosphatidylinositol signaling system, Vascular smooth muscle contraction, Wnt signaling pathway