Serum Amyloid P (APCS) Rabbit Polyclonal Antibody

CAT#: TA327226

Rabbit anti-APCS Polyclonal Antibody

Product Images

Western blot analysis of extracts of 293T cells, using APCS antibody.

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  Immunohistochemistry of paraffin-embedded rat lung using APCS antibody at dilution of 1:100 (40x lens).

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  Immunohistochemistry of paraffin-embedded human colon using APCS antibody at dilution of 1:100 (40x lens).

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  Immunohistochemistry of paraffin-embedded mouse brain using APCS antibody at dilution of 1:100 (40x lens).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50 - 1:100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human APCS
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: amyloid P component, serum
• Database Link:
  NP_001630
  Entrez Gene 20219 MouseEntrez Gene 29339 RatEntrez Gene 325 Human
  UniProt ID P02743
• Background: The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
• Synonyms: HEL-S-92n; PTX2; SAP

Reference Data

• Protein Families: Druggable Genome, Secreted Protein