PPP4C Rabbit Polyclonal Antibody

CAT#: TA327274

PPP4C Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using PPP4C antibody.

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  Immunohistochemistry of paraffin-embedded human lung cancer using PPP4C antibody at dilution of 1:200 (400x lens).

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  Immunohistochemistry of paraffin-embedded human stomach cancer using PPP4C antibody at dilution of 1:200 (400x lens).

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  Immunohistochemistry of paraffin-embedded rat lung using PPP4C antibody at dilution of 1:200 (400x lens).

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  Immunohistochemistry of paraffin-embedded rat spleen using PPP4C antibody at dilution of 1:200 (400x lens).

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Specifications

Product Data

• Applications: IHC, IP, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human PPP4C
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: protein phosphatase 4 catalytic subunit
• Database Link:
  NP_002711
  Entrez Gene 56420 MouseEntrez Gene 171366 RatEntrez Gene 5531 Human
  UniProt ID P60510
• Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4) is a putative member of a novel PP family.
• Synonyms: PP-X; PP4; PP4C; PPH3; PPP4; PPX

Reference Data

• Protein Families: Druggable Genome, Phosphatase