Sorbitol Dehydrogenase (SORD) Rabbit Polyclonal Antibody

CAT#: TA327281

Rabbit anti-SORD Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using SORD antibody.

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  Immunohistochemistry of paraffin-embedded rat lung using SORD antibody at dilution of 1:200 (200x lens).

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  Immunofluorescence analysis of MCF7 cell using SORD antibody. Blue: DAPI for nuclear staining.

Specifications

Product Data

• Applications: ICC/IF, IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200;IF 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human SORD
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: sorbitol dehydrogenase
• Database Link:
  NP_003095
  Entrez Gene 20322 MouseEntrez Gene 24788 RatEntrez Gene 6652 Human
  UniProt ID Q00796
• Background: SORD(Sorbitol dehydrogenase) is also named as L-iditol 2-dehydrogenase and belongs to the zinc-containing alcohol dehydrogenase family. It catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase, makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications. This protein can form a homotetramer.
• Synonyms: HEL-S-95n; SORD1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Fructose and mannose metabolism, Metabolic pathways