PPP2R2A Rabbit Polyclonal Antibody

CAT#: TA327323

Rabbit anti-PPP2R2A Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using PPP2R2A antibody.

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  Immunohistochemistry of paraffin-embedded rat brain using PPP2R2A antibody at dilution of 1:100 (200x lens).

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  Immunohistochemistry of paraffin-embedded rat spleen using PPP2R2A antibody at dilution of 1:100 (200x lens).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:500 - 1:2000;IHC 1:50- 1:200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human PPP2R2A
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: protein phosphatase 2 regulatory subunit Balpha
• Database Link:
  NP_002708
  Entrez Gene 71978 MouseEntrez Gene 117104 RatEntrez Gene 5520 Human
  UniProt ID P63151
• Background: Protein phosphatase 2A subunit B isoform R2-a (PPP2R2A) is the component of regulatory subunit B of serine/threonine protein phosphatase 2A (PP2A). PPP2R2A belongs to the R2/B55/PR55 family of regulatory subunit B. Evidence suggests that subunit PPP2R2A enhances TGF-β, Activin, and Nodal signaling pathways and may play an important role in cell cycle regulation. PPP2R2A/PP2A, B55-a/PR55-a isoform interacts with the type I TGF-β receptors via unique WD-40 repeats that contribute to the anti-proliferative function of TGF-β receptors.
• Synonyms: B55A; B55ALPHA; PR52A; PR55A

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Tight junction