NIRF (UHRF2) Rabbit Polyclonal Antibody

CAT#: TA327339

UHRF2 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using UHRF2 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human UHRF2
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 90 kDa
• Gene Name: ubiquitin like with PHD and ring finger domains 2
• Database Link:
  NP_690856
  Entrez Gene 109113 MouseEntrez Gene 309331 RatEntrez Gene 115426 Human
  UniProt ID Q96PU4
• Background: This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]
• Synonyms: NIRF; RNF107; TDRD23; URF2

Reference Data

• Protein Families: Druggable Genome, Transcription Factors