H3FT (HIST3H3) Rabbit Polyclonal Antibody
Frequently bought together (2)
Other products for "H3-4"
Specifications
Product Data | |
Applications | ChIP, ICC/IF, IHC, IP, WB |
Recommended Dilution | WB 1:500 - 1:1000;IHC 1:50- 1:100;IF 1:50- 1:200;IP 1:50- 1:200;ChIP 1:50- 1:200 |
Reactivities | Human, Mouse, Rat, Other (Wide Range) |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthetic peptideof human Histone H3K79me2 |
Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | histone cluster 3, H3 |
Database Link | |
Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. |
Synonyms | g; H3; H3.4; H3FT; H3t |
Reference Data | |
Protein Pathways | Systemic lupus erythematosus |
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