FLIP (CFLAR) Rabbit Polyclonal Antibody

CAT#: TA327380

CFLAR Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of Jurkat cell line, using CFLAR antibody.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB,1:500 - 1:2000
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 55kDa
• Gene Name: CASP8 and FADD like apoptosis regulator
• Database Link:
  NP_003870
  Entrez Gene 12633 MouseEntrez Gene 117279 RatEntrez Gene 8837 Human
  UniProt ID O15519
• Background: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.
• Synonyms: c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CASH; CASP8AP1; Casper; CLARP; FLAME; FLAME-1; FLAME1; FLIP

Reference Data

• Protein Families: Druggable Genome, Protease
• Protein Pathways: Apoptosis