PDX1 Rabbit Polyclonal Antibody

CAT#: TA327504

Rabbit anti-PDX1 Polyclonal Antibody

Product Images

Western blot analysis of extracts of Mouse intestines tissue, using PDX1 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB 1:500 - 1:1000
• Reactivities: Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide of human PDX1
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 31 kDa
• Gene Name: pancreatic and duodenal homeobox 1
• Database Link:
  NP_000200
  Entrez Gene 18609 Mouse
  UniProt ID P52945
• Background: The protein encoded by this gene is a transcriptional activator of several genes; including insulin; somatostatin; glucokinase; islet amyloid polypeptide; and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis; which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM); as well as maturity onset diabetes of the young type 4 (MODY4).
• Synonyms: GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1

Reference Data

• Protein Families: Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
• Protein Pathways: Maturity onset diabetes of the young, Type II diabetes mellitus