SLC1A4 Rabbit Polyclonal Antibody

CAT#: TA327511

SLC1A4 Rabbit Polyclonal Antibody

Product Images

Western blot analysis of extracts of HepG2 cell lines, using SLC1A4 antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500-1:2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide of human SLC1A4
• Formulation: Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: solute carrier family 1 member 4
• Database Link:
  NP_003029
  Entrez Gene 55963 MouseEntrez Gene 305540 RatEntrez Gene 6509 Human
  UniProt ID P43007
• Background: SLC1A4, also known as ASCT1, is a neutral amino acid transporter. Its other name, ASCT1, was given because it mediates obligatory exchange of alanine, serine, cysteine, and threonine. SLC1A4 mediates the efflux of glutamate from the neuron into the synaptic junction via calcium-independent release, as well as mediating the efflux of L-serine from glial cells and its uptake by neurons. SLC1A4-mediated transport is shown to involve a symmetrical potassium-independent electroneutral exchange of neutral amino acids and sodium, such that the current activated during transport is carried only by chloride ions.
• Synonyms: ASCT1; SATT; SPATCCM

Reference Data

• Protein Families: Druggable Genome, Transmembrane