alpha 1 Antitrypsin (SERPINA1) Rabbit Polyclonal Antibody

CAT#: TA327602

Rabbit Polyclonal A-1 Antitrypsin Antibody

Product Images

Immunohistochemistry staining of Paraffin Tonsil tissue by A-1 Antitrypsin antibody (dilution: 1:500 - 1:2000; visualization of staining: Cytoplasmic)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 1:500 - 1:2000
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: serpin family A member 1
• Database Link:
  NP_000286
  Entrez Gene 5265 Human
  UniProt ID P01009
• Synonyms: A1A; A1AT; AAT; alpha1AT; PI; PI1; PRO2275
• Note: The immunohistochemical staining of alpha-1-antitrypsin is considered to be very useful in the study of inherited AAT deficiency, benign and malignant hepatic tumors, and yolk sac carcinomas. Positive staining for A-1-antitrypsin may also be used in detection of benign and malignant lesions of an histiocytic nature. Sensitivity and specificity of the results have made this antibody a useful tool in the screening of patients with cryptogenic cirrhosis or other forms of liver disease with portal fibrosis of uncertain etiology.

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
• Protein Pathways: Complement and coagulation cascades