Calponin (CNN1) Rabbit Monoclonal Antibody [Clone ID: EP798Y]

CAT#: TA327614

Rabbit Monoclonal Calponin-1 Antibody

Product Images

Immunohistochemistry staining of Paraffin Appendix tissue by Calponin-1 antibody (dilution: 1:50 - 1:200; visualization of staining: Cytoplasmic)

Specifications

Product Data

• Clone Name: EP798Y
• Applications: IHC
• Recommended Dilution: IHC: 1:50 - 1:200
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: calponin 1
• Database Link:
  NP_001290
  Entrez Gene 1264 Human
  UniProt ID P51911
• Synonyms: HEL-S-14; Sm-Calp; SMCC
• Note: Calponin is a 34 kD polypeptide that interacts with actin, tropomyosin, and calmodulin. It is involved in smooth muscle contraction mechanism and is restricted exclusively to smooth muscle tissue. Anti-calponin has been found to be useful in staining myoepithelium and is therefore useful for differentiating benign sclerosing adenosis of the breast from infiltrating ductal carcinoma. Calponin positivity has also been noted in malignant myoepithelioma and pleomorphic adenoma of salivary gland origin as well as angiomatoid malignant fibrous histiocytoma.