CD10 (MME) Mouse Monoclonal Antibody [Clone ID: 56C6]

CAT#: TA327616

Mouse Monoclonal MME (CD10) Antibody

Product Images

Immunohistochemistry staining of Paraffin Kidney, tonsil tissue by CD10 antibody (dilution: 1:10 - 1:50; visualization of staining: Cytoplasmic, membranous)

Specifications

Product Data

• Clone Name: 56C6
• Applications: IHC
• Recommended Dilution: IHC: 1:10 - 1:50
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: membrane metallo-endopeptidase
• Database Link:
  NP_009218
  Entrez Gene 4311 Human
  UniProt ID P08473
• Synonyms: CALLA; CD10; CMT2T; NEP; SCA43; SFE
• Note: The antibody against CD10, common acute lymphoblastic leukemia antigen (CALLA), is a useful marker for the characterization of leukemias and lymphomas. This antibody labels lymphoblastic, Burkitt, and follicular lymphomas. Also, anti-CD10 detects the antigen of glomerular epithelial cells and the brush border of the proximal tubules; this characteristic may be helpful in interpreting renal ontogenesis in conjunction with other markers. Other non-lymphoid cells that are reactive with anti-CD10 are breast myoepithelial cells, bile canaliculi, neutrophils, stromal cells of bone marrow, and fibroblasts. Therefore, anti-CD10 has been used in classification of carcinomas, lymphomas, and leukemias.

Reference Data

• Protein Families: Druggable Genome, Protease, Transmembrane
• Protein Pathways: Alzheimer's disease, Hematopoietic cell lineage, Renin-angiotensin system