CD30 (TNFRSF8) Mouse Monoclonal Antibody [Clone ID: Ber-H2]

CAT#: TA327634

Mouse Monoclonal TNFRSF8 (CD30) Antibody

Product Images

Immunohistochemistry staining of Paraffin Classic Hodgkin lymphoma tissue by CD30 antibody (dilution: 1:50 - 1:200; visualization of staining: Membranous)

Specifications

Product Data

• Clone Name: Ber-H2
• Applications: IHC
• Recommended Dilution: IHC: 1:50 - 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Formulation: The antibody is diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <1% sodium azide.
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: tumor necrosis factor receptor superfamily member 8
• Database Link:
  NP_001234
  Entrez Gene 943 Human
  UniProt ID P28908
• Synonyms: CD30; D1S166E; Ki-1
• Note: Anti-CD30 detects a formalin-resistant epitope that is expressed by Reed-Sternberg cells in classic Hodgkin lymphoma, the majority of anaplastic large cell lymphomas, primary cutaneous CD30 positive T-cell lymphoproliferative disorders, and in embryonal carcinomas. Occasionally diffuse large B-cell lymphoma stains with this antibody. This antibody also stains plasma cells in paraffin-embedded tissue. However, reactive immunoblasts are immunoreactive with this antibody. The staining pattern of anti-CD30 in lymphoma or embryonal carcinoma is different, with the former being membranous and exhibiting Golgi zone accentuation in location, and the latter being membranous only.

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction