CD31 (PECAM1) Mouse Monoclonal Antibody [Clone ID: JC70]

CAT#: TA327635

Mouse Monoclonal PECAM1 (CD31) Antibody

Product Images

Immunohistochemistry staining of Paraffin Tonsil tissue by CD31 antibody (dilution: 1:25 - 1:100; visualization of staining: Cytoplasmic, membranous)

Specifications

Product Data

• Clone Name: JC70
• Applications: IHC
• Recommended Dilution: IHC: 1:25 - 1:100
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: platelet and endothelial cell adhesion molecule 1
• Database Link:
  NP_000433
  Entrez Gene 5175 Human
  UniProt ID P16284
• Synonyms: CD31; EndoCAM; endoCAM; GPIIA; PECA1; PECAM-1
• Note: CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Endothelial cells also express this marker, therefore, antibodies to CD31 have been used as a tool to identify the vascular origin of neoplasms. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) has not been observed with this antibody.

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration