CD5 Mouse Monoclonal Antibody [Clone ID: 4C7]

CAT#: TA327644

Mouse Monoclonal CD5 Antibody

Product Images

Immunohistochemistry staining of Paraffin Tonsil tissue by CD5 antibody (dilution: 1:10 - 1:50; visualization of staining: Membranous)

Specifications

Product Data

• Clone Name: 4C7
• Applications: IHC
• Recommended Dilution: IHC: 1:10 - 1:50
• Reactivities: Human
• Host: Mouse
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: CD5 molecule
• Database Link:
  NP_055022
  Entrez Gene 921 Human
  UniProt ID P06127
• Synonyms: LEU1; T1
• Note: Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Hematopoietic cell lineage