CDX2 Rabbit Monoclonal Antibody [Clone ID: EPR2764Y]

CAT#: TA327657

Rabbit Monoclonal CDX2 Antibody


USD 730.00

5 Days*

Size
    • 1 ml

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Specifications

Product Data
Clone Name EPR2764Y
Applications IHC
Recommended Dilution IHC: 1:100 - 1:500
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Monoclonal
Formulation This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name caudal type homeobox 2
Synonyms AS; CDX-3; CDX2; CDX3
Note CDX-2 is a caudal-related homeobox transcription factor whose expression in the adult is normally restricted to the intestinal epithelium. It is implicated in the development and maintenance of the intestinal mucosa. This protein is expressed immunohistochemically in the nuclei of normal intestinal epithelium. CDX-2 protein expression has been seen in gastrointestinal (GI) carcinomas, more so in lower GI than in upper GI. Anti-CDX-2 has been useful to establish gastrointestinal origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also stain positively with this antibody, which limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma versus mucinous carcinoma of the ovary.
Reference Data
Protein Families Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.