Chromogranin A (CHGA) Mouse Monoclonal Antibody [Clone ID: LK2H10]

CAT#: TA327660

Mouse Monoclonal Chromogranin A Antibody

Product Images

Immunohistochemistry staining of Paraffin Pancreas tissue by Chromogranin A antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic)

Specifications

Product Data

• Clone Name: LK2H10
• Applications: IHC
• Recommended Dilution: IHC: 1:100 - 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: chromogranin A
• Database Link:
  NP_001266
  Entrez Gene 1113 Human
  UniProt ID P10645
• Synonyms: CGA
• Note: Immunohistochemical methods have localized chromogranin in a wide variety of endocrine tissues such as the pituitary, pancreas, hypothalamus, and parathyroid. Neuroendocrine cells exhibit a fine granular immunoreactivity to anti-chromogranin. It is generally accepted that the co-expression of certain keratins and chromogranin mean neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

Reference Data

• Protein Families: Druggable Genome, Secreted Protein