Cytokeratin 20 (KRT20) Mouse Monoclonal Antibody [Clone ID: Ks20.8]

CAT#: TA327665

Mouse Monoclonal Cytokeratin 20 Antibody

Product Images

Immunohistochemistry staining of Paraffin Colon carcinoma tissue by Cytokeratin 20 antibody (dilution: 1:200 - 1:500; visualization of staining: Cytoplasmic)

Specifications

Product Data

• Clone Name: Ks20.8
• Applications: IHC
• Recommended Dilution: IHC: 1:200 - 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Formulation: The antibody is diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <1% sodium azide.
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: keratin 20
• Database Link:
  NP_061883
  Entrez Gene 54474 Human
  UniProt ID P35900
• Synonyms: CD20; CK-20; CK20; K20; KRT21
• Note: This antibody reacts primarily with gastric and intestinal epithelium, urothelium, and Merkel cells. Anti-cytokeratin 20 is useful in the differentiation of specific types of simple epithelial cells of the urinary tract as well as normal and malignantly transformed epithelia. Studies have identified the presence of cytokeratin 20 in adenocarcinomas of the colon, stomach, pancreas, and biliary system. Additionally, mucinous ovarian tumors, transitional cell, and Merkel cell carcinomas have shown reactivity. In contrast, squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas are non-reactive.