Cytokeratin 5 (KRT5) Mouse Monoclonal Antibody [Clone ID: D5/16B4]

CAT#: TA327667

Mouse Monoclonal Cytokeratin 5&6 Antibody


USD 560.00

5 Days*

Size
    • 1 ml

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Specifications

Product Data
Clone Name D5/16B4
Applications IHC
Recommended Dilution IHC: 1:50 - 1:200
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Formulation This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name keratin 5
Synonyms CK5; DDD; DDD1; EBS2; K5; KRT5A
Note Anti-CK 5 & 6 positivity is seen in nearly 100% of malignant mesotheliomas and in nearly 0% of lung adenocarcinomas. Anti-CK 5 & 6 positivity can be seen in undifferentiated large cell carcinoma as well as squamous carcinoma, and has been useful in recognizing spindle cell squamous cell carcinoma of the skin. Less than 10% of carcinomas of the breast, colon, and prostate stain positively for this marker. Anti-CK 5 & 6 has also been used successfully as a myoepithelial cell marker in the prostate and breast to determine malignancy. Anti-CK 5 & 6 is a useful marker to distinguish lung squamous cell carcinoma from lung adenocarcinoma and large cell carcinoma within a panel including antibodies against TTF-1, Napsin A, p63, SOX2, desmocollin3, and desmoglein3.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.