Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: B22.1&B23.1]

CAT#: TA327669

Mouse Monoclonal Cytokeratin 8&18 Antibody

Product Images

Immunohistochemistry staining of Paraffin Prostate, salivary gland tissue by Cytokeratin 8&18 antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic)

Specifications

Product Data

• Clone Name: B22.1&B23.1
• Applications: IHC
• Recommended Dilution: IHC: 1:100 - 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: keratin 8
• Database Link:
  NP_002264
  Entrez Gene 3856 Human
  UniProt ID P05787
• Synonyms: CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
• Note: Cytokeratins 8 & 18 (CK 8 & 18) can be found in most simple epithelia, e.g. thyroid, female breast, gastrointestinal tract, and respiratory tract. Adenocarcinomas and most non-keratinizing squamous carcinomas will stain with anti-CK 8 & 18, but keratinizing squamous carcinomas will not. This antibody is used when attempting to demonstrate the presence of Paget cells; there is very little keratin 18 in the normal epidermis so this will only stain Paget cells. The use of immunostaining facilitates the interpretation and has been shown to be more sensitive than mucin histochemistry.

Reference Data

• Protein Families: Druggable Genome