E Cadherin (CDH1) Rabbit Monoclonal Antibody [Clone ID: EP700Y]

CAT#: TA327671

Rabbit Monoclonal e-cadherin Antibody


USD 665.00

5 Days*

Size
    • 1 ml

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Specifications

Product Data
Clone Name EP700Y
Applications IHC
Recommended Dilution IHC: 1:50 - 1:200
Reactivities Human
Host Rabbit
Isotype IgG
Clonality Monoclonal
Formulation This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name cadherin 1
Synonyms Arc-1; CD324; CDHE; ECAD; LCAM; UVO
Note E-cadherin is an adhesion protein that is expressed in cells of epithelial lineage. Anti-E-cadherin stains positively in glandular epithelium as well as adenocarcinomas of the lung, G.I. tract, and ovary. Another application involves the differentiation of ductal (which stains positive) vs. lobular cancer of the breast. It has also been shown to be positive in some thyroid carcinomas. Loss of E-cadherin expression has been suggested as a poor prognostic sign in breast carcinoma and non-small cell lung carcinoma.
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Adherens junction, Bladder cancer, Cell adhesion molecules (CAMs), Endometrial cancer, Melanoma, Pathogenic Escherichia coli infection, Pathways in cancer, Thyroid cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.