MUM1 (IRF4) Rabbit Monoclonal Antibody [Clone ID: MRQ-43]

CAT#: TA327705

Rabbit Monoclonal MUM1 Antibody

Product Images

Immunohistochemistry staining of Paraffin Tonsil tissue by MUM1 antibody (dilution: 1:100 - 1:500; visualization of staining: Nuclear, cytoplasmic)

Specifications

Product Data

• Clone Name: MRQ-43
• Applications: IHC
• Recommended Dilution: IHC: 1:100 - 1:500
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG1
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: interferon regulatory factor 4
• Database Link:
  NP_001182215
  Entrez Gene 3662 Human
  UniProt ID Q15306
• Synonyms: LSIRF; MUM1; NF-EM5; SHEP8
• Note: MUM1 (multiple myeloma oncogene-1)/IRF4 (interferon regulatory factor 4) is a 50 kDa protein encoded by MUM1 gene, and a member of the interferon regulatory factor family of transcription factors. MUM1/IRF4 is expressed in the nuclei of plasma cells and a small percentage of germinal center (GC) B-cells located in the “light zone”. This antibody stains MUM1 protein, which is expressed in a subset of B-cells in the light zone of the germinal center, plasma cells, activated T-cells, and a wide spectrum of related hematolymphoid neoplasms derived from these cells. Therefore, this antibody is useful for the subclassification of lymphoid malignancies and an excellent marker for Reed-Sternberg cells of classic Hodgkin disease in combination with anti-CD30.

Reference Data

• Protein Families: Druggable Genome, Transcription Factors