smooth muscle Myosin heavy chain 11 (MYH11) Mouse Monoclonal Antibody [Clone ID: SMMS-1]

CAT#: TA327710

Mouse Monoclonal Myosin, Smooth Muscle Antibody

Product Images

Immunohistochemistry staining of Paraffin Breast tissue by Myosin, Smooth Muscle antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic)

Specifications

Product Data

• Clone Name: SMMS-1
• Applications: IHC
• Recommended Dilution: IHC: 1:100 - 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: myosin, heavy chain 11, smooth muscle
• Database Link:
  NP_001035202
  Entrez Gene 4629 Human
  UniProt ID P35749
• Synonyms: AAT4; FAA4; SMHC; SMMHC
• Note: Smooth Muscle Myosin, heavy chain (SMMS-1) is a cytoplasmic structural protein that is a major component of the contractile apparatus of the smooth muscle cells. SMMS-1 is also a myoepithelium-associated protein. Anti-SMMS-1 is a mouse monoclonal antibody to smooth muscle myosin, heavy chain that reacts with human visceral and vascular smooth muscle cells. The antibody also reacts with human myoepithelial cells. It is very helpful in distinguishing between benign sclerosing breast lesions and infiltrating carcinomas in difficult cases since it strongly stains the myoepithelial layer in the benign lesions while it is negative in the infiltrating carcinomas.

Reference Data

• Protein Pathways: Tight junction, Vascular smooth muscle contraction, Viral myocarditis