Prolactin (PRL) Rabbit Polyclonal Antibody

CAT#: TA327728

Rabbit Polyclonal Prolactin Antibody

Product Images

Immunohistochemistry staining of Paraffin Pituitary tissue by Prolactin antibody (dilution: 1:100 - 1:500; visualization of staining: Cytoplasmic)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 1:100 - 1:500
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: prolactin
• Database Link:
  NP_000939
  Entrez Gene 5617 Human
  UniProt ID P01236
• Synonyms: GHA1
• Note: Prolactin (PRL) is a single-chain polypeptide of 226 amino acids with a molecular weight of about 24 kD. Prolactin plays a role in multiple processes including cell growth, reproduction, and immune function. The pituitary hormone PRL is involved in tumorigenesis in rodents and humans. PRL promotes proliferation, survival, and migration of cancer cells acting via the PRL receptor.Anti-prolactin is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with prolactin- producing cells. Such prolactin-producing cells can also be found in prostate epithelium.

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction