Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: ER-PR8]

CAT#: TA327729

Mouse Monoclonal PSA Antibody

Product Images

Immunohistochemistry staining of Paraffin Prostate tissue by PSA antibody (dilution: 1:50 - 1:200; visualization of staining: Cytoplasmic)

Specifications

Product Data

• Clone Name: ER-PR8
• Applications: IHC
• Recommended Dilution: IHC: 1:50 - 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: kallikrein related peptidase 3
• Database Link:
  NP_001639
  Entrez Gene 354 Human
  UniProt ID P07288
• Synonyms: APS; hK3; KLK2A1; PSA
• Note: PSA is an antigen present in prostate tissue and in the majority of prostate carcinomas. This antibody recognizes primary and metastatic prostatic neoplasms and rarely tumors of nonprostatic origin. These include breast and a minority of salivary gland tumors. The antigen is a 33-34 kD glycoprotein that is restricted to epithelial cells of the prostate. An immunohistochemical study showed more than 95% of prostatic carcinomas stained with anti-PSA. PSA is demonstrable in the cytoplasm of acinar and ductal cells of benign prostate and prostate adenocarcinoma.

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein
• Protein Pathways: Pathways in cancer, Prostate cancer