S100A1 Mouse Monoclonal Antibody [Clone ID: 4C4.9]

CAT#: TA327733

Mouse Monoclonal S-100 Antibody

Product Images

Immunohistochemistry staining of Paraffin Melanoma tissue by S-100 antibody (dilution: 1:50 - 1:200; visualization of staining: Cytoplasmic, nuclear)

Specifications

Product Data

• Clone Name: 4C4.9
• Applications: IHC
• Recommended Dilution: IHC: 1:50 - 1:200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Formulation: The antibody is diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <1% sodium azide.
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: S100 calcium binding protein A1
• Database Link:
  NP_006262
  Entrez Gene 6271 Human
  UniProt ID P23297
• Synonyms: S100; S100-alpha; S100A
• Note: S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein. Despite the fact that S-100 protein is an ubiquitous substance, its demonstration is of great value in the identification of several neoplasms, particularly melanomas.