Synaptophysin (SYP) Rabbit Monoclonal Antibody [Clone ID: MRQ-40]

CAT#: TA327740

Rabbit Monoclonal Synaptophysin Antibody

Product Images

Immunohistochemistry staining of Paraffin Pancreas tissue by Synaptophysin antibody (visualization of staining: Cytoplasmic)

Specifications

Product Data

• Clone Name: MRQ-40
• Applications: IHC
• Recommended Dilution: IHC:
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG1
• Clonality: Monoclonal
• Formulation: This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: synaptophysin
• Database Link:
  NP_003170
  Entrez Gene 6855 Human
  UniProt ID P08247
• Synonyms: MRX96; MRXSYP
• Note: Anti-synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal mucosa. Positive staining is seen in neurons of the brain, spinal cord, retina, Paneth cells in the gastrointestinal tract, and gastric parietal cells. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. The expression of synaptophysin is independent of the presence of NSE or other neuroendocrine markers. Anti-synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

Reference Data

• Protein Families: Secreted Protein, Transmembrane