Tartrate Resistant Acid Phosphatase (ACP5) Mouse Monoclonal Antibody [Clone ID: 9C5]

CAT#: TA327934

Mouse Monoclonal anti-tartrate-resistant acid phosphatase (TRAcP) Antibody

Product Images

Western blot analysis of recombinant human TRACP/PAP/ACP5 protein (lane 1) and PBMC (lane 2) using anti-TRACP antibody, clone 9C5.

Specifications

Product Data

• Clone Name: 9C5
• Applications: WB
• Recommended Dilution: WB, IHC, IP
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2b, kappa
• Clonality: Monoclonal
• Immunogen: TRAcP purified from hairy cell leukemia spleen tissue
• Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33 kD
• Gene Name: acid phosphatase 5, tartrate resistant
• Database Link:
  NP_001602
  Entrez Gene 11433 MouseEntrez Gene 25732 RatEntrez Gene 54 Human
  UniProt ID P13686
• Background: Serum tartrate-resistant acid phosphatase exists as two isoforms (TRAcP5a and 5b). They are derived by differential-posttranslational processing of a common gene. Serum TRAcP5a is secreted by macrophages and dendritic cells and increased in many patients of rheumatoid arthritis. Serum TRAcP5b is produced from osteoclasts and elevated during bone resorption. In addition, this antibody labels hairy leukemia cells with high degree of sensitivity and specificity.
• Synonyms: HPAP; TRACP5a; TRACP5b; TRAP; TrATPase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysosome, Riboflavin metabolism