TIMP1 Mouse Monoclonal Antibody [Clone ID: F31P2A5]

CAT#: TA327965

Mouse Monoclonal anti-TIMP-1 Antibody

Product Images

Western blot analysis of recombinant human TIMP-1 protein using anti-TIMP-1, clone F31P2A5.

Specifications

Product Data

• Clone Name: F31P2A5
• Applications: WB
• Recommended Dilution: WB, IHC, ELISA
• Reactivities: Human, Monkey
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Ovalbumin-conjugated synthetic Peptide FQALGDAADIR
• Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
• Concentration: lot specific
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 23 kD
• Gene Name: TIMP metallopeptidase inhibitor 1
• Database Link:
  NP_003245
  Entrez Gene 574348 MonkeyEntrez Gene 7076 Human
  UniProt ID P01033
• Background: TIMP-1 (Tissue inhibitor of metalloproteinase 1) is a glycoprotein that belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain, predicted molecular weight 23 kD. TIMP-1 forms complexes with matrix metalloproteinases (MMPs) and inhibits the proteolytic activity of these enzymes. High levels TIMP-1 protein has been found in several types of cancers including breast cancer and this increase associated with a poor patient prognosis. TIMP-1 has also been implicated in the inhibition of apoptosis, promotion of growth, and process of angiogenesis. TIMP-1 may be useful as a prognostic marker in combination with urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1). Clone F31P2A5 has been shown to be useful for western blotting, immunohistochemistry and ELISA of human and monkey TIMP-1.
• Synonyms: CLGI; EPA; EPO; HCI; TIMP; TIMP-1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein