TIMP1 Mouse Monoclonal Antibody [Clone ID: F31P2A5]

CAT#: TA327965

Mouse Monoclonal anti-TIMP-1 Antibody


USD 240.00

5 Days*

Size
    • 100 ug

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Specifications

Product Data
Clone Name F31P2A5
Applications WB
Recommended Dilution WB, IHC, ELISA
Reactivities Human, Monkey
Host Mouse
Isotype IgG1, kappa
Clonality Monoclonal
Immunogen Ovalbumin-conjugated synthetic Peptide FQALGDAADIR
Formulation This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
Concentration lot specific
Purification The antibody was purified by affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 23 kD
Gene Name TIMP metallopeptidase inhibitor 1
Background TIMP-1 (Tissue inhibitor of metalloproteinase 1) is a glycoprotein that belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain, predicted molecular weight 23 kD. TIMP-1 forms complexes with matrix metalloproteinases (MMPs) and inhibits the proteolytic activity of these enzymes. High levels TIMP-1 protein has been found in several types of cancers including breast cancer and this increase associated with a poor patient prognosis. TIMP-1 has also been implicated in the inhibition of apoptosis, promotion of growth, and process of angiogenesis. TIMP-1 may be useful as a prognostic marker in combination with urokinase plasminogen activator (uPA) and plasminogen activator inhibitor type-1 (PAI-1). Clone F31P2A5 has been shown to be useful for western blotting, immunohistochemistry and ELISA of human and monkey TIMP-1.
Synonyms CLGI; EPA; EPO; HCI; TIMP; TIMP-1
Reference Data
Protein Families Druggable Genome, Secreted Protein

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.