TIMP2 Mouse Monoclonal Antibody [Clone ID: F27P3A4]

CAT#: TA327966

Mouse Monoclonal anti-TIMP-2 Antibody

Product Images

Western blot analysis of recombinant human TIMP-2 protein using anti-TIMP-2, clone F27P3A4.

Specifications

Product Data

• Clone Name: F27P3A4
• Applications: WB
• Recommended Dilution: WB, IHC, ELISA
• Reactivities: Human, Mouse, Rabbit, Chicken, Zebrafish
• Host: Mouse
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Immunogen: Ovalbumin-conjugated synthetic Peptide DSGNDIYGNPI
• Formulation: This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
• Concentration: lot specific
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 24 kD
• Gene Name: TIMP metallopeptidase inhibitor 2
• Database Link:
  NP_003246
  Entrez Gene 21858 MouseEntrez Gene 7077 Human
  UniProt ID P16035
• Background: TIMP-2 (Tissue inhibitor of metalloproteinase 2) is a nonglycosylated protein that belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain, predicted molecular weight 24 kD. The mechanisms of TIMPs inhibit angiogenesis appear to be specific for each member of the TIMP family. TIMP-2 binds to the surface of human endothelial cells through interaction with the integrin α3β1, and abrogates angiogenic factor induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition. Clone F27P3A4 has been shown to be useful for western blotting, immunohistochemistry and ELISA of human, mouse, rabbit, chicken, zebrafish, and pig TIMP-2.
• Synonyms: CSC-21K; DDC8

Reference Data

• Protein Families: Druggable Genome, Secreted Protein