GRP78 (HSPA5) Rat Monoclonal Antibody [Clone ID: 76-E6]

CAT#: TA328008

Rat Monoclonal anti-mouse BiP Antibody

Product Images

Hela cell extract was resolved by electrophoresis, transferred to nitrocellulose and probed with monoclonal anti-mouse BiP antibody. Proteins were visualized using a goat anti-rat secondary conjugated to HRP and a chemiluminescence system.

Specifications

Product Data

• Clone Name: 76-E6
• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human, Mouse
• Host: Rat
• Isotype: IgG2a, kappa
• Clonality: Monoclonal
• Immunogen: Mouse BiP:u chain complexes
• Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
• Concentration: lot specific
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 78 KD
• Gene Name: heat shock protein family A (Hsp70) member 5
• Database Link:
  NP_005338
  Entrez Gene 14828 MouseEntrez Gene 3309 Human
  UniProt ID P11021
• Background: Originally identified as an immunoglobulin heavy chain-binding protein in pre-B cells, BiP was found to be involved in stress responses and also as a molecular chaperone in intracellular protein transport, prevention of protein toxicity and direction of protein folding and assembly in the endoplasmic reticulum. Because so many ER proteins interact transiently with BiP, it may play a key role in monitoring protein transport through the cell.
• Synonyms: BIP; GRP78; HEL-S-89n; MIF2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Antigen processing and presentation, Prion diseases