PTBP1 Mouse Monoclonal Antibody [Clone ID: 3H7]

CAT#: TA328040

Mouse Monoclonal anti-PTBP1 Antibody

Product Images

Extracts from human PBMC were resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody against PTBP1 (clone 3H7). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and a chemiluminescence detection system.

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  Formalin-fixed paraffin-embedded human kidney tissue was stained with 3H7 at 15 ug/ml and developed with an alkaline phosphatase chromogen substrate (red color). Tissue was counterstained with H&E (blue/pink). Magnification, 40X.

Specifications

Product Data

• Clone Name: 3H7
• Applications: IHC, WB
• Recommended Dilution: WB, IHC
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Recombinant human PTBP1 (full length)
• Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
• Concentration: lot specific
• Purification: The antibody was purified by affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 59.6 kD
• Gene Name: polypyrimidine tract binding protein 1
• Database Link:
  NP_114367
  Entrez Gene 5725 Human
  UniProt ID P26599
• Background: The 3H7 monoclonal antibody recognizes human PTBP1 also known as Polypyrimidine tract binding protein 1, Heterogeneous nuclear ribonucleoprotein I, and 57 kD RNA-binding protein. PTBP1 is a ubiquitously expressed nuclear protein with a predicted molecular weight approximately 59.6 kD. The polypyrimidine tract binding protein (PTB) is an important regulator of alternative splicing that also affects mRNA localization, stabilization, polyadenylation, and translation. PTBP1 has been shown to interact with FUS, Caspase3, PKCa, Raver1, and HnRNP-L protein. The PTB gene contains 15 exons and spans 13.5 kb. The 3H7 antibody has been shown to be useful for Western blotting.
• Synonyms: HNRNP-I; HNRNPI; HNRPI; pPTB; PTB; PTB-1; PTB-T; PTB2; PTB3; PTB4

Reference Data

• Protein Families: Druggable Genome