Semaphorin 7a (SEMA7A) Rabbit Polyclonal Antibody

CAT#: TA328118

Rabbit polyclonal anti-SEMA7A antibody (N-term)

Product Images

SEMA7A Antibody (N-term) (Cat. #TA328118) western blot analysis in human placenta and mouse testis tissue lysates (35ug/lane).This demonstrates the SEMA7A antibody detected the SEMA7A protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This SEMA7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-202 amino acids from the N-terminal region of human SEMA7A.
• Formulation: PBS with 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: semaphorin 7A (John Milton Hagen blood group)
• Database Link:
  NP_003603
  Entrez Gene 20361 MouseEntrez Gene 8482 Human
  UniProt ID O75326
• Background: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
• Synonyms: CD108; CDw108; H-SEMA-K1; H-Sema-L; JMH; SEMAK1; SEMAL

Reference Data

• Protein Pathways: Axon guidance