PCNA Mouse Monoclonal Antibody [Clone ID: 1157CT1.1.3]

CAT#: TA328131

Mouse monoclonal anti-PCNA antibody (C-term)

Product Images

PCNA Antibody (C-term) (Cat. #TA328131) western blot analysis in Hela, mouse L929 and rat C6 cell line lysates (35ug/lane).This demonstrates the PCNA antibody detected the PCNA protein (arrow).

Specifications

Product Data

• Clone Name: 1157CT1.1.3
• Applications: WB
• Recommended Dilution: WB: 1:2000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: This PCNA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 236-261 amino acids from the C-terminal region of human PCNA.
• Formulation: PBS with 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: proliferating cell nuclear antigen
• Database Link:
  NP_872590
  Entrez Gene 18538 MouseEntrez Gene 25737 RatEntrez Gene 718006 MonkeyEntrez Gene 5111 Human
  UniProt ID P12004
• Background: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
• Synonyms: ATLD2

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair