Fas Ligand (FASLG) Goat Polyclonal Antibody

CAT#: TA328307

Anti-Human sFas Ligand Goat Polyclonal Antibody

Product Images

This antibody stained formalin-fixed, paraffin-embedded sections of human angiosarcoma. The recommended concentration is 0.75 ug/mL - 2.5 ug/mL with an overnight incubation at 4C. An HRP-labeled polymer detection system was used with a AB chromogen. Heat induced antigen retrieval with a pH 6.0 sodium citrate buffer is recommended. Optimal concentrations and conditions may vary.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: WB: 0.1-0.2ug/mL, ELISA: 0.25-2ug/mL, IHC: 0.25ug/mL - 1mg/mL
• Reactivities: Human
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: CHO cell derived recombinant Human sFas Ligand.
• Formulation: A sterile filtered antibody solution was lyophilized from PBS, pH 7.2.
• Purification: Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hsFasL/Apo1L. Anti-Human sFasL/Apo1L specific antibody was purified by affinity chromatography employing immobilized hsFasL/Apo1L matrix.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: Fas ligand
• Database Link:
  NP_000630
  Entrez Gene 356 Human
  UniProt ID P48023
• Synonyms: ALPS1B; APT1LG1; APTL; CD95-L; CD95L; CD178; FASL; TNFSF6
• Note: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of sFasL/Apo1L (10 ng/ml), a concentration of 0.08 - 0.1 <=ug/ml of this antibody is required.

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Allograft rejection, Apoptosis, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Pathways in cancer, Type I diabetes mellitus