PAI1 (SERPINE1) Rabbit Polyclonal Antibody

CAT#: TA328413

Anti-Human PAI-1 Rabbit Polyclonal Antibody

Product Images

This antibody stained formalin-fixed, paraffin-embedded sections of human breast invasive ductal carcinoma. The recommended concentration is 62.5 ng/ml with an overnight incubation at 4C. An HRP-labeled polymer detection system was used with a DAB chromogen. Heat induced antigen retrieval with a pH 6.0 sodium citrate buffer is recommended. Optimal concentrations and conditions may vary. *Additional Immunostaining data available. Please contact Tech Support for information.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: WB: 0.1-0.2ug/mL, ELISA: 0.25-2ug/mL, IHC: 0.25ug/mL - 1mg/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: E.coli derived Recombinant Human PAI-1
• Formulation: A sterile filtered antibody solution was lyophilized from PBS, pH 7.2.
• Purification: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hPAI-1 (human Plasminogen Activator Inhibitor-1). Anti-Human PAI-1 specific antibody was purified by affinity chromatography employing immobilized hPAI-1 matrix.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: serpin family E member 1
• Database Link:
  NP_000593
  Entrez Gene 5054 Human
  UniProt ID P05121
• Synonyms: PAI; PAI-1; PAI1; PLANH1
• Note: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of hPAI-1 (4.5 ug/ml), a concentration of at least 15.0 ug/ml of this antibody is required.

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades, p53 signaling pathway