Cacng2 Rabbit Polyclonal Antibody

CAT#: TA328729

Rabbit Polyclonal Anti-CaVgamma2

Product Images

Western blot analysis of rat brain membranes: 1. Anti-Cav?2 antibody, (1:200). 2. Anti-Cav?2 antibody, preincubated with the control peptide antigen.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:200-1:2000; FC: 1:50-1:600
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide (C)RATDYLQASAITRIPS, corresponding to amino acid residues 213-228 of mouse Cav?2. Intracellular, C-terminus.
• Formulation: Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
• Purification: Affinity purified on immobilized antigen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: calcium channel, voltage-dependent, gamma subunit 2
• Database Link:
  NP_031609
  Entrez Gene 10369 HumanEntrez Gene 84347 RatEntrez Gene 12300 Mouse
  UniProt ID O88602
• Background: The ? subunit protein is an auxiliary subunit of the CaV (voltage dependent calcium) channel multimer complex. ?1 was first identified in skeletal muscle as a part of the proteins complex purified as the DHP receptor. Eight ? subunit isoforms were identified in mammalian genoms and they share some sequence as well as structure homology.1 ? subunit contains four transmembrane helixes, with intracellular N and C termini. Usually their association with the pore-forming a1 subunit results in reduced current amplitude.CaV?2 is also known as stargazin, and interacts and regulates the activity and trafficking of AMPA glutamate receptors.
• Synonyms: MGC138502; MGC138504; stargazin