Glra3 Rabbit Polyclonal Antibody

CAT#: TA328848

Rabbit Polyclonal Anti-Glycine Receptor alpha3

Product Images

Western blot analysis of rat brain membranes: 1. Anti-Glycine Receptor a3 antibody, (1:200). 2. Anti-Glycine Receptor a3 antibody, preincubated with the control peptide antigen.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:200-1:2000
• Reactivities: Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide (C)KNKTEAFALEKFYR, corresponding to amino acid residues 355-368 of rat Glycine Receptor a3. 2nd intracellular loop.
• Formulation: Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
• Purification: Affinity purified on immobilized antigen.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: glycine receptor, alpha 3
• Database Link:
  NP_446176
  Entrez Gene 114516 Rat
• Background: Glycine is a major neurotransmitter in the mammalian central nervous system.The glycine receptor is a ligand gated Cl- channel, mediating synaptic inhibition in the spinal cord, retina and regions of the brain.The glycine receptor is a pentamer consisting of a and Ã? subunits.To date there are four known a-subunit isoforms (a1- a4) encoded by different genes.In humans, two alternative splice variants of the glycine receptor a3 have been described: a3L, and a3K where the a3L splice variant bears an additional segment of 15 amino acids within the long cytoplasmic TM3-4 loop. These variants differ in their desensitization kinetics.
• Synonyms: GLRA3