P2rx6 Rabbit Polyclonal Antibody

CAT#: TA329001

Rabbit polyclonal Anti-P2X6 Receptor

Product Images

Western blot analysis of rat brain membranes: 1. Anti-P2X6 Receptor antibody, (1:200). 2. Anti-P2X6 Receptor antibody, preincubated with the control peptide antigen.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:200-1:2000; IHC: 1:100-1:3,000; FC: 1:50-1:600
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Peptide (C)RTKYEEARAPKATTNSA, corresponding to amino acid residues 363-379 of rat P2X6 Receptor?. Intracellular, C-terminus.
• Formulation: Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
• Purification: Affinity purified on immobilized antigen.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: purinergic receptor P2X 6
• Database Link:
  NP_036853
  Entrez Gene 9127 HumanEntrez Gene 18440 MouseEntrez Gene 25041 Rat
  UniProt ID P51579
• Background: The P2X receptors belong to the ligand-gated ion channel family and are activated by extracellular ATP. P2X receptors are involved in synaptic communication and in diseases of the nervous system. The P2X receptors family consist of at least seven isoforms: P2X1-P2X7. All P2X subunits can assemble to form homomeric or heteromeric functional channels with the exception of P2X6, which only seems to function as part of a heteromeric complex. The P2X6 receptor assembles to a heteromultimer with two other P2X subunits, P2X2 and P2X4. The P2X6 receptor is extensively expressed throughout the central nervous system.
• Synonyms: MGC129625; P2RXL1; P2X6; P2XM