n-Myc (MYCN) Rabbit Polyclonal Antibody

CAT#: TA329756

Rabbit Polyclonal Anti-MYCN Antibody

Product Images

WB Suggested Anti-MYCN Antibody Titration: 2.5 ug/ml; Positive Control: Human heart

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-MYCN antibody: synthetic peptide directed towards the C terminal of human MYCN. Synthetic peptide located within the following region: EDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILER
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 50 kDa
• Gene Name: v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
• Database Link:
  NP_005369
  Entrez Gene 4613 Human
  UniProt ID P04198
• Background: MYCN is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. It is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas
• Synonyms: bHLHe37; MODED; N-myc; NMYC; ODED
• Note: Immunogen sequence homology: Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Pig: 92%; Rat: 92%; Rabbit: 77%

Reference Data

• Protein Families: Druggable Genome, Transcription Factors