RNF40 Rabbit Polyclonal Antibody

CAT#: TA329845

Rabbit Polyclonal Anti-RNF40 Antibody

Product Images

WB Suggested Anti-RNF40 Antibody Titration: 1.25 ug/ml; Positive Control: 293T cell lysate RNF40 is supported by BioGPS gene expression data to be expressed in HEK293T

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  Human Muscle

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  Sample Type : Adult mouse cerebellum (l0x) sectionPrimary Antibody Dilution : 1:100Secondary Antibody : Donkey Anti-rabbit (568 nm)Secondary Antibody Dilution : 1:500 Color/Signal Descriptions : RNF40: Red DAPI:BlueGene Name : RNF40 Submitted by : Anonymo

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB, IHC
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-RNF40 antibody: synthetic peptide directed towards the C terminal of human RNF40. Synthetic peptide located within the following region: KLLREEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELT
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 114 kDa
• Gene Name: ring finger protein 40
• Database Link:
  NP_055586
  Entrez Gene 9810 Human
  UniProt ID O75150
• Background: RNF40 contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
• Synonyms: BRE1B; RBP95; STARING
• Note: Immunogen sequence homology: Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 100%; Zebrafish: 85%

Reference Data

• Protein Families: Druggable Genome