Ptges2 Rabbit Polyclonal Antibody

CAT#: TA329982

Rabbit Polyclonal Anti-Ptges2 Antibody

Product Images

Host: Rabbit; Target Name: Ptges2; Sample Tissue: Mouse Spleen lysates; Antibody Dilution: 1.0 ug/ml

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-Ptges2 antibody is: synthetic peptide directed towards the middle region of Mouse Ptges2. Synthetic peptide located within the following region: GAAAMYLISKRLKSRHHLQDDVRVDLYEAANKWVTAVGKDRPFMGGQKPN
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43 kDa
• Gene Name: prostaglandin E synthase 2
• Database Link:
  NP_598544
  Entrez Gene 96979 Mouse
  UniProt ID Q8BWM0
• Background: The protein encoded by this gene is a Golgi membrane-associated prostaglandin E synthase candidate, which is capable of catalyzing the conversion of prostaglandin H2 to prostaglandin E2 in vitro. However, a study using mice deficient of this gene suggests that this enzyme does not contribute to prostaglandin E2 biosynthesis in vivo. This protein is synthesized as a Golgi membrane-bound protein, but its N-terminal hydrophobic region is cleaved off during protein maturation to produce the predominant soluble truncated form that still retains the enzyme activity. This soluble protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE), possibly via an interaction with CAAAT/enhancer-binding protein-beta.
• Synonyms: C9orf15; FLJ14038; GBF1; MGC11289; mPGES-2; PGES2
• Note: Immunogen sequence homology: Rat: 100%; Horse: 100%; Mouse: 100%; Pig: 93%; Guinea pig: 93%; Bovine: 92%; Dog: 86%; Human: 79%