TCF3 / E2A (TCF3) Rabbit Polyclonal Antibody

CAT#: TA330106

Rabbit Polyclonal Anti-TCF3 Antibody

Product Images

WB Suggested Anti-TCF3 Antibody Titration: 5.0ug/ml; Positive Control: Jurkat cell lysateTCF3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-TCF3 antibody: synthetic peptide directed towards the C terminal of human TCF3. Synthetic peptide located within the following region: EENTSAADHSEEEKKELKAPRARTSPDEDEDDLLPPEQKAEREKERRVAN
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 48 kDa
• Gene Name: transcription factor 3
• Database Link:
  NP_001129611
  Entrez Gene 6929 Human
  UniProt ID P15923
• Background: TCF3 contains 1 basic helix-loop-helix (bHLH) domain. Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. TCF3 binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.
• Synonyms: AGM8; bHLHb21; E2A; E47; ITF1; TCF-3; VDIR
• Note: Immunogen sequence homology: Dog: 100%; Guinea pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Chicken: 93%; Pig: 92%

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors